‘The happiest plant on Earth’

Everything you need to know about kanna – from its use in Indigenous healing to its role combating modern-day health challenges
Katie Hill - Editor-in-Chief, My Green Pod
Kanna growing in South Africa

This article first appeared in our Earth Day 2025 issue of My Green Pod Magazine, published 22 April. Click here to subscribe to our digital edition and get each issue delivered straight to your inbox

Stephanie Wang discovered kanna back in 2013, during her first shamanic plant medicine ceremony.

‘I felt my heart expand more than I ever imagined possible’, she remembers. ‘The feeling was accompanied by a deep sense of acceptance and belonging.’

Stephanie’s experience was so profound that she felt moved to share it; ‘I felt my mission emerge’, she tells us; ‘a mission to help make this plant medicine accessible to as many people as possible.’

Stephanie founded KA! Empathogenics as a way to fulfil this goal, and support her broader mission to usher in the next revolution in mental health – a revolution powered by plants.

‘Our mission is to restore full-spectrum aliveness for all beings’, Stephanie shares. ‘My goal in founding KA! Empathogenics has been to help people feel more alive, connected and capable as they navigate the challenges of their daily lives with more consciousness and love. I want to create a more heart-centred world and kanna is the perfect plant ally for that.’

What is kanna?

Kanna is a succulent plant with small flowers, typically white or yellow, that is native to the Karoo desert in South Africa and Namibia.

It is increasingly cultivated for commercial use due to its medicinal properties as a mood-enhancing plant.

The plant is an empathogen (increasing feelings of empathy and connection), a euphoriant (producing feelings of joy), an anxiolytic (releasing stress and tension), an adaptogen (regulating your nervous system) a nootropic (protecting brain health), an aphrodisiac (we know you know this one), a hypnotic (inducing healthy, natural sleep) and is ergogenic (enhancing physical performance and stamina).

It also has anti-inflammatory, antioxidant, antimicrobial and immunomodulatory properties.

A number of studies conducted over the last 30 years confirm kanna’s benefits for anxiety and stress reduction as well as cognitive support, but until relatively recently, kanna has received minimal scientific attention.

‘Kanna has been clinically proven to reduce stress, bring calm and improve focus and cognition, helping people feel more relaxed and open-hearted, with a sense of grounded energy, and better able to connect with themselves, others and nature’, Stephanie explains.

The plant has been dubbed ‘nature’s MDMA’, but while both are empathogens, meaning they increase feelings of empathy, acceptance and connection, the similarities end there.

While it affects mental processes, kanna is sober and won’t make you feel ‘high’. It is also non-addictive and its many alkaloids work to curb excessive cravings and behaviours.

It helps to take you out of an overactive fight-or-flight response, and build mental and emotional resilience.

Like coffee, kanna is psychoactive but not psychedelic; it affects the mind and mood but is not hallucinogenic, nor will it alter perception or sense of time.

Kanna is also adaptogenic, balancing your system over time without being toxic to your liver.

All of this makes kanna a very special plant; it will probably come as no surprise that it has a rich history of traditional use among Indigenous peoples in South Africa.

Plant-based healing

The bushmen and Khoi people have used kanna for at least 2,000 years, and maybe even for several thousand.

Archeological evidence has been found in cave sites from the Later Stone Age, some even connected to human settlements from about 1,000-2,000 BC.

‘The first written records we have about kanna come from Dutch colonists in the 17th century, who saw the Indigenous people chewing it and noticed the positive effects on their mood’, Stephanie says.

Just as R. Gordon Wasson’s experiences with Mazatec healer María Sabina in Mexico in 1955 introduced psilocybin mushrooms to western audiences, and Albert Hofmann’s discovery of LSD was based on work with sacred plants used by Indigenous peoples, kanna’s use among Indigenous peoples in South Africa has inspired interest among western practitioners who see ceremony and community integration as central to healing.

‘Indigenous healing practices take a holistic approach, recognising the interconnectedness of physical, mental, spiritual and social wellbeing’, Stephanie shares. ‘Traditional healers focus on treating the whole person rather than just isolated symptoms, as is common in western medicine.’

A core principle of Indigenous healing is the significance of connection to community, ancestors, nature and spiritual forces. Illness is often viewed as a result of spiritual imbalance, social disharmony or ancestral influence.

‘Plants are highly revered as medicine and are believed to possess their own spirit and agency’, Stephanie says. ‘Knowledge is typically held by community members and passed down orally through generations. The goal of treatment is to restore harmony, not simply eliminate symptoms.’

For Stephanie, connection is fundamental to healing and a core principle of KA!’s mission – yet it’s something we lack as a society.

‘Connection provides emotional resilience’, Stephanie explains. ‘When we feel connected to ourselves, others and nature, our bodies release oxytocin and reduce stress hormones, directly affecting our immune response and healing capacity. Social connection has been linked to faster recovery times and reduced inflammation, in addition to its emotional benefits.’

For Stephanie, this is where western medicine gets it wrong; it often emphasises isolated, standardised treatments and a more mechanistic view of the body. Even when western medicine adopts herbal remedies, it often strips away the cultural context and holistic framework for commercial purposes.

This approach clearly isn’t working – according to the mental health charity Mind, one in four people will experience a mental health problem of some kind each year in England.

Healthy connections

With the well-documented rise of physical and mental illnesses in the west, it’s no surprise that Stephanie has seen increased interest around kanna from both scientific and consumer perspectives.

‘In general, there’s a rise in consumer interest in plant-based alternatives to pharmaceutical medications’, she shares; ‘kanna is the only non-pharmaceutical, 100% natural supplement that treats anxiety by enhancing the effects of neurotransmitter GABA (like a benzodiazepine) and treats depression by increasing serotonin (like an SSRI) simultaneously. We are also seeing increased awareness of traditional medicines from around the world, and of course the psychedelic renaissance has created curiosity about ethnobotanicals.’

Kanna supports a sense of wellbeing and promotes empathy and connection – the lack of which is the root of many physical and mental ailments.

When taken as a natural remedy it can help you relax and become more in tune with yourself, others and the environment around you. It also helps to reduce stress and anxiety and lift mood, while supporting focus and productivity.

When to avoid kanna

Kanna is a versatile and gentle plant that is suitable to take whenever you feel like it, so there are no rules when it comes to working with this plant. 

Stephanie recommends taking one KA! Daily Chew in the morning and re-upping with a dose of the tincture in the afternoon, or before any heart-opening or grounding activity.

‘Experiment with different times of day and various dosages and situations in your life to find what works best for you’, Stephanie says (see ‘Ways to take kanna’ box for ideas).

Stephanie does not recommend taking kanna with monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), norepinephrine and dopamine reuptake inhibitors (NDRIs), benzodiazepines or central nervous system (CNS) depressants without medical supervision by a qualified healthcare professional.

Since kanna acts as a natural serotonin re-uptake inhibitor, if you take kanna with medication that raises the level of serotonin there could be a risk of serotonin syndrome due to having too much serotonin in your system.

Consult your healthcare provider before use if you have a medical condition or if you are taking any prescription medications.

Priming your system

It’s important to find a high-quality source of kanna since variations in potency and form can produce wildly different effects.

‘Make sure to differentiate between kanna herb and kanna extract’, Stephanie advises. ‘Extracts are much more potent because they are concentrated. Find out the alkaloid content of the kanna – alkaloids are naturally occurring compounds, mostly found in plants, that affect the central nervous system, so the higher the alkaloid content, the more potent its effects.’

For some people it can take time for the effects of kanna to be felt, so you may need to prime your system by working with it consistently over a few weeks and then taking a break for a week to notice what has shifted for you. 

‘It takes most people between five and 30 days of regular kanna intake to get fully primed, and the transformative effects of KA!’s Daily Chews are best experienced with daily intake for 30 days or more’, Stephanie says. ‘That is why we host a 30 Day Kanna Microdosing Journey Into the Heart to guide people through their first 30 days taking kanna, and learn how to collaborate with this plant in a way that maximises the benefits.’

All the superplants that are part of KA! Empathogenics’ scientific formulation, including the kanna, are sustainably grown, ethically sourced and of premium quality. ‘Our kanna extract is created from a specific species of the kanna plant with optimal alkaloid content, producing a standardised extract of uniquely high potency’, Stephanie explains. 

Grown in reciprocity

Kanna often grows in desert environments, and requires significantly fewer resources than conventional crops. It has been harvested traditionally for centuries, though today kanna is commercially cultivated on farms to meet demand.

‘The kanna used in making our Kanna Chews and Tincture is grown in farms and does not endanger kanna in the wild’, Stephanie says. ‘It is grown without pesticides, synthetic fertilisers or any conventional farming practices that could compromise the purity of the extracts. Our growers adhere to strict protocols during every phase of the cultivation process in order to preserve previous natural resources and to minimise waste.’

Reciprocity is also part of Stephanie’s mission; the kanna is sourced from a supplier in South Africa who has a profit-sharing programme with the Indigenous, and Stephanie has started sponsoring cultural preservation and education projects with local bushmen and Khoi leaders, with the intention to develop a sustainable give-back programme.

‘We make all our products in-house and do not use a co-packer, which allows us to uphold the highest quality standards’, Stephanie says. ‘We use a patent-pending heatless production process: no heat means no degradation – which leaves our plant ingredients’ bioactivity fully intact, unlike conventional gummies.’

All KA! products are also free of sugars, elastomers, artificial sweeteners, gluten, animal products, caffeine, ‘natural’ flavours and preservatives – they don’t even contain citric acid.

Kanna was key to Stephanie’s healing journey, catalysing her personal growth and deepening her connection with the wisdom of plants.

As we look for alternative ways to address the challenges of modern life, this special plant could be the solution many are looking for.

WAYS TO TAKE KANNA

  • In the morning before work to help set the tone for a calm and productive day.
  • Mid-afternoon, a few hours after lunch, when you need an energetic pick-me-up.
  • For an added boost of inspired creativity and focus.
  • Instead of having alcohol after work to unwind and take the edge off. Kanna has been referred to as onse droë drank, meaning ‘our dry drink’ in certain Khoi-descendent cultures in South Africa.
  • Before meditation to instantly presence your mind, body and spirit.
  • Before bodywork like massage, deep tissue work or fascia-releasing therapies.
  • With your partner or friends, since kanna eases communication, softens social edges and can enhance intimacy.
  • With family to enhance mood and increase openness.
  • Before a tough or deep conversation to centre you in your feelings and create more empathy for others.
  • Before solo or team sports. There’s a reason Indigenous bushmen would chew on kanna’s roots to sustain and focus their energies during multi-day hunts.
  • In nature, for deeper attunement to the natural rhythms of life.

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